I’ve had a standing desk at home for a few years now, and I can safely say I’m still a fan. My friend Zak switched to one at home recently and he mentioned that the first initial benefit is that it gets you away from the computer. I think this is still one of the primary benefits for me; instead of having the status quo of slouching in front of a screen as a desirable option, it forces you to reconsider and often choose reading a book on the couch. I feel it also has a tendency to increase energy levels.
If you spend all day at work sitting in front of a computer and then do the same at home, I would strongly recommend switching one of the environments to standing. I did mine with a cheap old IKEA desk with adjustable height shelves. Another key component has been one of those standing mats that cashiers sometimes have. A nice one is relatively expensive (more than the desk actually, like $200) but the few times I’ve stood without one my heels were feeling it pretty quickly, and not in a good way.